Brand  (β version)

PDB ID: 3S20

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Ligands
Code Name Style Show Link
CER (2s, 3r)-3-hydroxy-4-oxo-7,10-trans,trans-dodecadienamide PoSSuM
PEG Di(hydroxyethyl)ether PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 3S20   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal structure of cerulenin bound Xanthomonas campestri OleA (soak)
Release Data : 2012-05-16
Compound :
mol_id molecule chains
1 3-oxoacyl-[ACP] synthase III A,B
Source :
mol_id organism_scientific expression_system
1 Xanthomonas campestris pv. campestris  (taxid:340) Escherichia coli  (taxid:562)
gene: fabH, XCC0212
Authors : Goblirsch, B.R., Wilmot, C.M.
Keywords : Non-decarboxylative Claisen Condensation Reaction, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.8796 Å )
Citation :

Crystal Structures of Xanthomonas campestris OleA Reveal Features That Promote Head-to-Head Condensation of Two Long-Chain Fatty Acids.

Goblirsch, B.R.,Frias, J.A.,Wackett, L.P.  et al.
(2012)  Biochemistry  51 : 4138 - 4146

PubMed: 22524624
DOI: 10.1021/bi300386m

Reaction

Chain : A, B
UniProt : Q8PDX2 (OLEA_XANCP)
Reaction: EC: Evidence:
Physiological Direction:
a 1,2-saturated acyl-CoA + an acyl-CoA + H2O = an (R)-2-alkyl- 3-oxoalkanoate + 2 CoA + H(+) 2.3.3.20 PubMed:21266575, PubMed:22524624, PubMed:27815501
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