Het-PDB Navi2 (PDB: 3RJ1)

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Ligands
Code	Name		Style	Show	Link
SE	Selenium atom				PoSSuM

Non-standard Residues
Code	Name	Show
MSE	Selenomethionine

Glycosylation
Code	Name	Emphasize

Modification
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Download interaction data: 3RJ1

Code :

3RJ1 PDBj RCSB PDB PDBe

Header :

TRANSCRIPTION

Title :

Architecture of the Mediator Head module

Release Data :

2011-07-27

Compound :

mol_id	molecule	chains	synonym
1	Mediator of RNA polymerase II transcription subunit 11	A,H,O	Mediator complex subunit 11
	mutation: T16G, M17S

mol_id	molecule	chains	synonym
2	Mediator of RNA polymerase II transcription subunit 17	B,I,P	Mediator complex subunit 17, Suppressor of RNA polymerase B 4

mol_id	molecule	chains	synonym
3	Mediator of RNA polymerase II transcription subunit 8	C,J,Q	Mediator complex subunit 8

mol_id	molecule	chains	synonym
4	Mediator of RNA polymerase II transcription subunit 22	D,K,R	Mediator complex subunit 22, Suppressor of RNA polymerase B 6

mol_id	molecule	chains	synonym
5	Mediator of RNA polymerase II transcription subunit 18	E,L,S	Mediator complex subunit 18, Suppressor of RNA polymerase B 5

mol_id	molecule	chains	synonym
6	Mediator of RNA polymerase II transcription subunit 20	F,M,T	Hyper-recombination suppressor protein 2, Mediator complex subunit 20, Suppressor of RNA polymerase B 2

mol_id	molecule	chains	synonym
7	Mediator of RNA polymerase II transcription subunit 6	G,N,U	Mediator complex subunit 6

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Saccharomyces cerevisiae (taxid:4932)	Brewer's yeast,lager beer yeast,yeast	Trichoplusia ni (taxid:7111)
	gene: MED11, YMR112C, YM9718.11C expression_system_cell_line: Hi5 expression_system_vector_type: pFL + pUCDM + pSPL

mol_id	organism_scientific	organism_common	expression_system
2	Saccharomyces cerevisiae (taxid:4932)	Brewer's yeast,lager beer yeast,yeast	Trichoplusia ni (taxid:7111)
	gene: SRB4, MED17, YER022W expression_system_cell_line: Hi5 expression_system_vector_type: pFL + pUCDM + pSPL

mol_id	organism_scientific	organism_common	expression_system
3	Saccharomyces cerevisiae (taxid:4932)	Brewer's yeast,lager beer yeast,yeast	Trichoplusia ni (taxid:7111)
	gene: MED8, YBR193C, YBR1403 expression_system_cell_line: Hi5 expression_system_vector_type: pFL + pUCDM + pSPL

mol_id	organism_scientific	organism_common	expression_system
4	Saccharomyces cerevisiae (taxid:4932)	Brewer's yeast,lager beer yeast,yeast	Trichoplusia ni (taxid:7111)
	gene: SRB6, MED22, YBR253W, YBR1721 expression_system_cell_line: Hi5 expression_system_vector_type: pFL + pUCDM + pSPL

mol_id	organism_scientific	organism_common	expression_system
5	Saccharomyces cerevisiae (taxid:4932)	Brewer's yeast,lager beer yeast,yeast	Trichoplusia ni (taxid:7111)
	gene: SRB5, MED18, YGR104C expression_system_cell_line: Hi5 expression_system_vector_type: pFL + pUCDM + pSPL

mol_id	organism_scientific	organism_common	expression_system
6	Saccharomyces cerevisiae (taxid:4932)	Brewer's yeast,lager beer yeast,yeast	Trichoplusia ni (taxid:7111)
	gene: SRB2, HRS2, MED20, YHR041C expression_system_cell_line: Hi5 expression_system_vector_type: pFL + pUCDM + pSPL

mol_id	organism_scientific	organism_common	expression_system
7	Saccharomyces cerevisiae (taxid:4932)	Brewer's yeast,lager beer yeast,yeast	Trichoplusia ni (taxid:7111)
	gene: MED6, MTR32, YHR058C expression_system_cell_line: Hi5 expression_system_vector_type: pFL + pUCDM + pSPL

Authors :

Imasaki, T., Calero, G., Cai, G., Tsai, K.L., Yamada, K., Cardelli, F., Erdjument-Bromage, H., Tempst, P., Berger, I., Kornberg, G.L., Asturias, F.J., Kornberg, R.D., Takagi, Y.

Keywords :

Mediator, RNA polymeras II, Pol II, RNAP, Med, Head module, Mediator Head, regulator, Helical bundle, transcriptional regulation, RNA polymerase II, TBP, nucleus, TRANSCRIPTION

Exp. method :

X-RAY DIFFRACTION ( 4.300 Å )

Citation :

Architecture of the Mediator head module.

Imasaki, T.,Calero, G.,Cai, G. et al.
(2011) Nature 475 : 240 - 243

PubMed: 21725323
DOI: 10.1038/nature10162

Chain :	A, H, O
UniProt :	Q99278 (MED11_YEAST)
Reaction :	-

Chain :	B, I, P
UniProt :	P32569 (MED17_YEAST)
Reaction :	-

Chain :	C, J, Q
UniProt :	P38304 (MED8_YEAST)
Reaction :	-

Chain :	D, K, R
UniProt :	P32570 (MED22_YEAST)
Reaction :	-

Chain :	E, L, S
UniProt :	P32585 (MED18_YEAST)
Reaction :	-

Chain :	F, M, T
UniProt :	P34162 (MED20_YEAST)
Reaction :	-

Chain :	G, N, U
UniProt :	P38782 (MED6_YEAST)
Reaction :	-

PDB ID: 3RJ1

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