Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
ACT Acetate ion
FUZ 2-[(furan-2-ylmethyl)amino]benzoic acid
IMD Imidazole
ZN Zinc ion
Code : 3RF5
Header : ISOMERASE/ISOMERASE INHIBITOR
Title : Ancylostoma ceylanicum mif in complex with N-(2,3,4,5,6-pentafluoro-benzyl)-4-sulfamoyl-benzamide
Release Data : 2011-10-12
Compound :
mol_id molecule chains
1 Macrophage migration inhibitory factor A,B,C
fragment: UNP RESIDUES 2-117
Source :
mol_id organism_scientific expression_system
1 Ancylostoma ceylanicum  (taxid:53326) Escherichia coli  (taxid:469008)
expression_system_strain: BL21(DE3)
expression_system_vector_type: PLASMID
expression_system_plasmid: PET22B
Authors : Cho, Y., Lolis, E.
Keywords : PROTEIN-SMALL MOLECULE COMPLEX, ISOMERASE, ISOMERASE-ISOMERASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 2.10 Å )
Citation :

Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors.

Cho, Y.,Vermeire, J.J.,Merkel, J.S.  et al.
(2011)  Chem.Biol.  18 : 1089 - 1101

PubMed: 21944748
DOI: 10.1016/j.chembiol.2011.07.011

Chain : A, B, C
UniProt : A4GRE3 (No found in current UniProtKB/SwissProt)
Reaction : -