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Ligands
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DOG Digoxigenin
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Code : 3RA7   PDBj   RCSB PDB   PDBe
Header : IMMUNE SYSTEM
Title : Bispecific digoxigenin binding antibodies for targeted payload delivery
Release Data : 2011-07-20
Compound :
mol_id molecule chains
1 Fab fragment, light chain L,M
mol_id molecule chains
2 Fab fragment, heavy chain H,I
Source :
mol_id organism_scientific organism_common expression_system
1 Mus musculus  (taxid:10090) Mouse Homo sapiens  (taxid:9606)
expression_system_common: Human
expression_system_cell_line: HEK293
mol_id organism_scientific organism_common expression_system
2 Mus musculus  (taxid:10090) Mouse Homo sapiens  (taxid:9606)
expression_system_common: Human
expression_system_cell_line: HEK293
Authors : Hopfner, K.P., Lammens, A.
Keywords : Fab fragment, Antibody Engineering, Cancer, targeted payload delivery, IMMUNE SYSTEM
Exp. method : X-RAY DIFFRACTION ( 2.798 Å )
Citation :

Bispecific digoxigenin-binding antibodies for targeted payload delivery

Metz, S.,Haas, A.K.,Daub, K.  et al.
(2011)  Proc.Natl.Acad.Sci.USA  108 : 8194 - 8199

PubMed: 21536919
DOI: 10.1073/pnas.1018565108