PDB ID: 3R5R
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Structure summary
Code : | 3R5R PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE | ||||||||||||
Title : | Structure of Ddn, the Deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824, with co-factor F420 | ||||||||||||
Release Data : | 2012-01-18 | ||||||||||||
Compound : |
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Source : |
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Authors : | Cellitti, S.E., Shaffer, J., Jones, D.H., Mukherjee, T., Gurumurthy, M., Bursulaya, B., Boshoff, H.I.M., Choi, I., Nayya, A., Lee, Y.S., Cherian, J., Niyomrattanakit, P., Dick, T., Manjunatha, U.H., Barry, C.E., Spraggon, G., Geierstanger, B.H. | ||||||||||||
Keywords : | PA-824, split barrel-like fold, DUF385, Deazaflavin-dependent nitroreductase, co-factor, nitroimidazoles, OXIDOREDUCTASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.1010 Å ) | ||||||||||||
Citation : |
Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824.
Cellitti, S.E.,Shaffer, J.,Jones, D.H.
et al.
PubMed: 22244759 |
Reaction
Chain : | A, B, C, D, E |
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UniProt : | P71854 |
Reaction : | - |