Brand  (β version)

PDB ID: 3Q80

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Ligands
Code Name Style Show Link
CDM 4-diphosphocytidyl-2-C-methyl-D-erythritol PoSSuM
CL Chloride ion PoSSuM
MG Magnesium ion PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 3Q80   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Structure of Mtb 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD) Complexed with CDP-ME
Release Data : 2011-05-04
Compound :
mol_id molecule chains synonym
1 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase A,B 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT
ec: 2.7.7.60
Source :
mol_id organism_scientific expression_system
1 Mycobacterium tuberculosis  (taxid:83332) Escherichia coli  (taxid:469008)
strain: H37Rv
gene: ispD, Rv3582c, MT3688, MTCY06G11.29c
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pET28b
Authors : Reddy, M.C.M., Bruning, J.B., Thurman, C., Ioerger, T.R., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)
Keywords : TB Structural Genomics Consortium, TBSGC, Rossmann fold, 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.0 Å )
Citation :

Crystal Structure of Mycobacterium tuberculosis 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD): a candidate antitubercular drug target

Reddy, M.C.M.,Bruning, J.B.,Thurman, C.  et al.
(2011)  Proteins 

Reaction

Chain : A, B
UniProt : P96864
Reaction : -