Het-PDB Navi2 (PDB: 3Q7J)

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Ligands
Code	Name		Style	Show	Link
ZN	Zinc ion				PoSSuM
FBO	L-phenylalanyl-n6-[(benzyloxy)carbonyl]-n1-hydroxy-L-lysinamide				PoSSuM

Non-standard Residues
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Download interaction data: 3Q7J

Code :

3Q7J PDBj RCSB PDB PDBe

Header :

HYDROLASE/HYDROLASE INHIBITOR

Title :

Engineered Thermoplasma Acidophilum F3 factor mimics human aminopeptidase N (APN) as a target for anticancer drug development

Release Data :

2011-07-27

Compound :

mol_id	molecule	chains
1	Tricorn protease-interacting factor F3	A,B
	ec: 3.4.11.- mutation: E101Q,N261T

Source :

mol_id	organism_scientific	expression_system
1	Thermoplasma acidophilum (taxid:273075)	Escherichia coli (taxid:562)
	strain: DSM 1728 gene: O93655, Ta0815, trf3 expression_system_strain: BL21(DE3) expression_system_vector_type: plasmid expression_system_plasmid: pET21b

Authors :

Su, J., Wang, Q., Feng, J., Zhang, C., Zhu, D., We, T., Xu, W., Gu, L.

Keywords :

Trf3, Inhibitor FBO, Aminopeptidase, Inhibitor binding, HYDROLASE-HYDROLASE INHIBITOR complex

Exp. method :

X-RAY DIFFRACTION ( 2.910 Å )

Citation :

Engineered Thermoplasma acidophilum factor F3 mimics human aminopeptidase N (APN) as a target for anticancer drug development

Su, J.,Wang, Q.,Feng, J. et al.
(2011) Bioorg.Med.Chem. 19 : 2991 - 2996

PDB ID: 3Q7J