Het-PDB Navi2 (PDB: 3PM1)

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Ligands
Code	Name		Style	Show	Link
ET	Ethidium				PoSSuM
SO4	Sulfate ion				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 3PM1

Code :

3PM1 PDBj RCSB PDB PDBe

Header :

TRANSCRIPTION

Title :

Structure of QacR E90Q bound to Ethidium

Release Data :

2011-07-13

Compound :

mol_id	molecule	chains
1	HTH-type transcriptional regulator qacR	B,A
	mutation: K67S, C72A, E90Q, C141S

Source :

mol_id	organism_scientific	expression_system
1	Staphylococcus aureus (taxid:158878)	Escherichia coli (taxid:668369)
	strain: Mu50 atcc: 700699 gene: qacR expression_system_strain: DH5[alpha] expression_system_vector_type: plasmid expression_system_plasmid: pet

Authors :

Schumacher, M.A.

Keywords :

TetR family member, transcription regulation, multidrug resistance, DNA, nucleoid, TRANSCRIPTION

Exp. method :

X-RAY DIFFRACTION ( 2.80 Å )

Citation :

A single acidic residue can guide binding site selection but does not govern QacR cationic-drug affinity.

Peters, K.M.,Brooks, B.E.,Schumacher, M.A. et al.
(2011) Plos One 6 : e15974 - e15974

PDB ID: 3PM1