PDB ID: 3PJ3
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Structure summary
Code : | 3PJ3 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/INHIBITOR | ||||||||||||
Title : | Crystal structure of BTK kinase domain complexed with 2-Methyl-5-[(E)-(3-phenyl-acryloyl)amino]-N-(2-phenyl-3H-imidazo[4,5-B]pyridin-6-yl)-benzamide | ||||||||||||
Release Data : | 2011-01-12 | ||||||||||||
Compound : |
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Source : |
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Authors : | Kuglstatter, A., Wong, A. | ||||||||||||
Keywords : | helix C-in, DFG-out, TRANSFERASE, TRANSFERASE-INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.85 Å ) | ||||||||||||
Citation : |
Insights into the conformational flexibility of Bruton's tyrosine kinase from multiple ligand complex structures.
Kuglstatter, A.,Wong, A.,Tsing, S.
et al.
PubMed: 21280133 |
Reaction
Chain : | A | ||||||||
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UniProt : | Q06187 (BTK_HUMAN) | ||||||||
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