Het-PDB Navi2 (PDB: 3PBO)

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Ligands
Code	Name		Style	Show	Link
CAZ	Acylated ceftazidime				PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

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Download interaction data: 3PBO

Code :

3PBO PDBj RCSB PDB PDBe

Header :

HYDROLASE/ANTIBIOTIC

Title :

Crystal structure of PBP3 complexed with ceftazidime

Release Data :

2010-12-22

Compound :

mol_id	molecule	chains
1	Penicillin-binding protein 3	A
	fragment: UNP Residues 50-579

Source :

mol_id	organism_scientific	expression_system
1	Pseudomonas aeruginosa (taxid:208964)	Escherichia coli (taxid:562)
	strain: PAO1 gene: ftsI, PA4418, pbpB

Authors :

Han, S.

Keywords :

PBP3, HYDROLASE-ANTIBIOTIC complex

Exp. method :

X-RAY DIFFRACTION ( 1.74 Å )

Citation :

Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of Pseudomonas aeruginosa.

Han, S.,Zaniewski, R.P.,Marr, E.S. et al.
(2010) Proc.Natl.Acad.Sci.USA 107 : 22002 - 22007

Chain :

UniProt :

Q51504 (Q51504_PSEAI)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
Preferential cleavage: (Ac)2-L-Lys-D-Ala-\|-D-Ala. Also transpeptidation of peptidyl-alanyl moieties that are N-acyl substituents of D-alanine.	3.4.16.4	HAMAP-Rule:MF_02080
	-	HAMAP-Rule:MF_02080

PDB ID: 3PBO