Brand  (β version)

PDB ID: 3P2R

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
FAH Fluoroacetic acid PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 3P2R   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Crystal structure of the fluoroacetyl-CoA-specific thioesterase FlK in complex with fluoroacetate
Release Data : 2010-10-20
Compound :
mol_id molecule chains
1 Fluoroacetyl coenzyme A thioesterase A,B
Source :
mol_id organism_scientific expression_system
1 Streptomyces cattleya  (taxid:29303) Escherichia coli  (taxid:562)
gene: flK
Authors : Weeks, A.M., Coyle, S.M., Jinek, M., Doudna, J.A., Chang, M.C.Y.
Keywords : hot dog-fold, thioesterase, HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 2.460 Å )
Citation :

Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.

Weeks, A.M.,Coyle, S.M.,Jinek, M.  et al.
(2010)  Biochemistry  49 : 9269 - 9279

PubMed: 20836570
DOI: 10.1021/bi101102u

Reaction

Chain : A, B
UniProt : Q1EMV2 (FLK_STRCT)
Reaction: EC: Evidence:
Physiological Direction:
fluoroacetyl-CoA + H2O = fluoroacetate + CoA + H(+) 3.1.2.29 PubMed:16720268, PubMed:20836570
-