Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
2M5 Methyl 7-deoxy-L-glycero-alpha-D-manno-heptopyranoside
CL Chloride ion
GOL Glycerol
Code : 3OAZ
Header : IMMUNE SYSTEM
Title : A non-self sugar mimic of the HIV glycan shield shows enhanced antigenicity
Release Data : 2011-01-12
Compound :
mol_id molecule chains
1 Fab 2G12, heavy chain H,M
fragment: Fab
mol_id molecule chains
2 Fab 2G12, light chain K,L
Source :
mol_id organism_scientific expression_system
1 Homo sapiens  (taxid:9606) Cricetulus griseus  (taxid:10029)
expression_system_common: Chinese hamster
expression_system_organ: ovary
mol_id organism_scientific expression_system
2 Homo sapiens  (taxid:9606) Cricetulus griseus  (taxid:10029)
expression_system_common: Chinese hamster
expression_system_organ: ovary
Authors : Doores, K.J., Fulton, Z., Hong, V., Patel, M.K., Scanlan, C.N., Wormald, M.R., Finn, M.G., Burton, D.R., Wilson, I.A., Davis, B.G.
Keywords : Fab, IMMUNE SYSTEM
Exp. method : X-RAY DIFFRACTION ( 1.7500 Å )
Citation :

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity.

Doores, K.J.,Fulton, Z.,Hong, V.  et al.
(2010)  Proc.Natl.Acad.Sci.USA  107 : 17107 - 17112

PubMed: 20852065
DOI: 10.1073/pnas.1002717107