PDB ID: 3O5X
Hetero Atom Contents
The number of atoms exceeds 100,000. So, it can not be displayed here.
Select unit:
Select hetatm:
Select chain: Sequence
Data format:
Color scheme of protein:
Structure summary
Code : | 3O5X PDBj RCSB PDB PDBe | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Header : | HYDROLASE | ||||||||||||
Title : | Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor | ||||||||||||
Release Data : | 2010-08-11 | ||||||||||||
Compound : |
|
||||||||||||
Source : |
|
||||||||||||
Authors : | Zhang, Z.-Y., Zhang, X., He, Y., Liu, S., Yu, Z., Jiang, Z., Yang, Z., Dong, Y., Nabinger, S.C., Wu, L., Gunawan, A.M., Wang, L., Chan, R.J. | ||||||||||||
Keywords : | SHP2-IIB-08 complex, inhibitor, binding affinity, binding selectivity, receptor, Hydrolase, Dephosphorylation | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.0 Å ) | ||||||||||||
Citation : |
Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2).
Zhang, X.,He, Y.,Liu, S.
et al.
PubMed: 20170098 |
Reaction
Chain : | A | ||||||||
---|---|---|---|---|---|---|---|---|---|
UniProt : | Q06124 (PTN11_HUMAN) | ||||||||
|