Brand  (β version)

color scheme of protein:


Code Name Link
OS Osmium ion
Modified Residues
Code Name Link
MSE Selenomethionine
Code : 3NYJ
Title : Crystal Structure Analysis of APP E2 domain
Release Data : 2011-06-01
Compound :
mol_id molecule chains synonym
1 Amyloid beta A4 protein A Alzheimer disease amyloid protein, ABPP, APPI, APP, PreA4, Cerebral vascular amyloid peptide, CVAP, Protease nexin-II, PN-II, N-APP, Soluble APP-alpha, S-APP-alpha, Soluble APP-beta, S-APP-beta, C99, Beta-amyloid protein 42, Beta-APP42, Beta-amyloid protein 40, Beta-APP40, C83, P3(42), P3(40), C80, Gamma-secretase C-terminal fragment 59, Gamma-CTF(59), Amyloid intracellular domain 59, AICD-59, AID(59), Gamma-secretase C-terminal fragment 57, Gamma-CTF(57), Amyloid intracellular domain 57, AICD-57, AID(57), Gamma-secretase C-terminal fragment 50, Gamma-CTF(50), Amyloid intracellular domain 50, AICD-50, AID(50), C31
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: A4, AD1, APP
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pET28
Authors : Ha, Y., Hu, J., Lee, S., Liu, X.
Keywords : Alzheimer's disease, helical hairpin, PROTEIN FIBRIL
Exp. method : X-RAY DIFFRACTION ( 3.2000 Å )
Citation :

The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization.

Lee, S.,Xue, Y.,Hu, J.  et al.
(2011)  Biochemistry  50 : 5453 - 5464

PubMed: 21574595
DOI: 10.1021/bi101846x

Chain : A
UniProt : P05067 (A4_HUMAN)
Reaction : -