Het-PDB Navi2 (PDB: 3NYJ)

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Ligands
Code	Name		Style	Show	Link
OS	Osmium ion				PoSSuM

Non-standard Residues
Code	Name	Show
MSE	Selenomethionine

Glycosylation
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Download interaction data: 3NYJ

Code :

3NYJ PDBj RCSB PDB PDBe

Header :

PROTEIN FIBRIL

Title :

Crystal Structure Analysis of APP E2 domain

Release Data :

2011-06-01

Compound :

mol_id	molecule	chains	synonym
1	Amyloid beta A4 protein	A	Alzheimer disease amyloid protein, ABPP, APPI, APP, PreA4, Cerebral vascular amyloid peptide, CVAP, Protease nexin-II, PN-II, N-APP, Soluble APP-alpha, S-APP-alpha, Soluble APP-beta, S-APP-beta, C99, Beta-amyloid protein 42, Beta-APP42, Beta-amyloid protein 40, Beta-APP40, C83, P3(42), P3(40), C80, Gamma-secretase C-terminal fragment 59, Gamma-CTF(59), Amyloid intracellular domain 59, AICD-59, AID(59), Gamma-secretase C-terminal fragment 57, Gamma-CTF(57), Amyloid intracellular domain 57, AICD-57, AID(57), Gamma-secretase C-terminal fragment 50, Gamma-CTF(50), Amyloid intracellular domain 50, AICD-50, AID(50), C31

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: A4, AD1, APP expression_system_strain: BL21(DE3) expression_system_vector_type: plasmid expression_system_plasmid: pET28

Authors :

Ha, Y., Hu, J., Lee, S., Liu, X.

Keywords :

Alzheimer's disease, helical hairpin, PROTEIN FIBRIL

Exp. method :

X-RAY DIFFRACTION ( 3.2000 Å )

Citation :

The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization.

Lee, S.,Xue, Y.,Hu, J. et al.
(2011) Biochemistry 50 : 5453 - 5464

PDB ID: 3NYJ