Brand  (β version)

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Ligands
Code Name Link
OS Osmium ion
ACT Acetate ion
NAG N-acetyl-D-glucosamine
Code : 3N44
Header : VIRAL PROTEIN
Title : Crystal structure of the mature envelope glycoprotein complex (trypsin cleavage; Osmium soak) of Chikungunya virus.
Release Data : 2010-12-01
Compound :
mol_id molecule chains
1 E3 envelope glycoprotein A
fragment: polyprotein fragment residues 266-319
mol_id molecule chains
2 E2 envelope glycoprotein B
fragment: polyprotein fragment residues 329-666
mol_id molecule chains
3 E1 envelope glycoprotein F
fragment: polyprotein fragment residues 810-1200
mutation: P1046A
Source :
mol_id organism_scientific organism_common expression_system
1 Chikungunya virus  (taxid:37124) CHIKV Drosophila Melanogaster  (taxid:7227)
strain: 05-115
expression_system_cell_line: SCHNEIDER 2
expression_system_vector_type: PLASMID
expression_system_plasmid: pMRBiP/V5 HisA
mol_id organism_scientific organism_common expression_system
2 Chikungunya virus  (taxid:37124) CHIKV Drosophila Melanogaster  (taxid:7227)
strain: 05-115
expression_system_cell_line: SCHNEIDER 2
expression_system_vector_type: PLASMID
expression_system_plasmid: pMRBiP/V5 HisA
mol_id organism_scientific organism_common expression_system
3 Chikungunya virus  (taxid:37124) CHIKV Drosophila Melanogaster  (taxid:7227)
strain: 05-115
expression_system_cell_line: SCHNEIDER 2
expression_system_vector_type: PLASMID
expression_system_plasmid: pMRBiP/V5 HisA
Authors : Voss, J., Vaney, M.C., Duquerroy, S., Rey, F.A.
Keywords : VIRAL PROTEIN, IMMATURE HETERODIMER, ALPHAVIRUS, RECEPTOR BINDING, MEMBRANE FUSION
Exp. method : X-RAY DIFFRACTION ( 2.35 Å )
Citation :

Glycoprotein organization of Chikungunya virus particles revealed by X-ray crystallography.

Voss, J.E.,Vaney, M.C.,Duquerroy, S.  et al.
(2010)  Nature  468 : 709 - 712

PubMed: 21124458
DOI: 10.1038/nature09555

Structure and interactions at the viral surface of the envelope protein E1 of Semliki Forest virus.

Roussel, A.,Lescar, J.,Vaney, M.C.  et al.
(2006)  Structure  14 : 75 - 86

PubMed: 16407067
DOI: 10.1016/j.str.2005.09.014

Conformational change and protein-protein interactions of the fusion protein of Semliki Forest virus.

Gibbons, D.L.,Vaney, M.C.,Roussel, A.  et al.
(2004)  Nature  427 : 320 - 325

PubMed: 14737160
DOI: 10.1038/nature02239

The Fusion glycoprotein shell of Semliki Forest virus: an icosahedral assembly primed for fusogenic activation at endosomal pH.

Lescar, J.,Roussel, A.,Wien, M.W.  et al.
(2001)  Cell(Cambridge,Mass.)  105 : 137 - 148

PubMed: 11301009

Structural Changes of Envelope Proteins During Alphavirus Fusion.

Li, L.,Jose, J.,Xiang, Y.  et al.
To be Published 

Chain : F
UniProt : Q1H8W5 (No found in current UniProtKB/SwissProt)
Reaction : -