Het-PDB Navi2 (PDB: 3MKS)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name	Link
SO4	Sulfate ion	PoSSuM
C1C	1,1'-binaphthalene-2,2'-dicarboxylic acid	PoSSuM
GOL	Glycerol	PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 3MKS

Code :

3MKS PDBj RCSB PDB PDBe

Header :

LIGASE/CELL CYCLE

Title :

Crystal Structure of yeast Cdc4/Skp1 in complex with an allosteric inhibitor SCF-I2

Release Data :

2010-07-21

Compound :

mol_id	molecule	chains	synonym
1	Suppressor of kinetochore protein 1	A,C	Centromere DNA-binding protein complex CBF3 subunit D, E3 ubiquitin ligase complex SCF subunit SKP1
	fragment: UNP Residues 2-194 with 37-64 deleted

mol_id	molecule	chains	synonym
2	Cell division control protein 4	B,D	F-box protein CDC4, E3 ubiquitin ligase complex SCF subunit CDC4
	fragment: UNP Residues 263-744 with 602-605 and 609-624 deleted

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Saccharomyces cerevisiae (taxid:4932)	Brewer's yeast,lager beer yeast,yeast	Escherichia coli (taxid:469008)
	gene: SKP1, CBF3D, YDR328C, D9798.14 expression_system_strain: BL21(DE3)codon plus expression_system_vector_type: plasmid expression_system_plasmid: pProEx

mol_id	organism_scientific	organism_common	expression_system
2	Saccharomyces cerevisiae (taxid:4932)	Brewer's yeast,lager beer yeast,yeast	Escherichia coli (taxid:469008)
	gene: CDC4, YFL009W expression_system_strain: BL21(DE3)codon plus expression_system_vector_type: plasmid expression_system_plasmid: pProEx

Authors :

Orlicky, S., Sicheri, F., Tyers, M., Tang, X.

Keywords :

ubiquitin ligase, protein binding, small molecule complex, LIGASE/CELL CYCLE, LIGASE-CELL CYCLE complex

Exp. method :

X-RAY DIFFRACTION ( 2.60 Å )

Citation :

An allosteric inhibitor of substrate recognition by the SCF(Cdc4) ubiquitin ligase.

Orlicky, S.,Tang, X.,Neduva, V. et al.
(2010) Nat.Biotechnol. 28 : 733 - 737

PDB ID: 3MKS