Brand  (β version)

PDB ID: 3MA7

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Ligands
Code Name Style Show Link
CD4 (2r,5r,11r,14r)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-2,14-bis(tetradecanoyloxy)-4,6,10,12,16-pentaoxa-5,11-diphosphatriacont-1-yl tetradecanoate PoSSuM
PLM Palmitic acid PoSSuM
Non-standard Residues
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Glycosylation
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NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
Modification
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Structure summary

Code : 3MA7   PDBj   RCSB PDB   PDBe
Header : IMMUNE SYSTEM
Title : Crystal structure of Cardiolipin bound to mouse CD1D
Release Data : 2011-03-16
Compound :
mol_id molecule chains
1 T-cell surface glycoprotein CD1d1 C,A
fragment: UNP RESIDUES 19-297
mol_id molecule chains
2 Beta-2 microglobulin D,B
fragment: UNP RESIDUES 21-119
Source :
mol_id organism_scientific organism_common expression_system
1 Mus musculus  (taxid:10090) Mouse SPODOPTERA FRUGIPERDA  (taxid:7108)
gene: Cd1.1, CD1D, Cd1d1
expression_system_common: Fall armyworm
expression_system_strain: SF9
expression_system_vector_type: BACULOVIRUS TRANSFER VECTOR
expression_system_plasmid: PBACPHP10
mol_id organism_scientific organism_common expression_system
2 Mus musculus  (taxid:10090) Mouse SPODOPTERA FRUGIPERDA  (taxid:7108)
gene: B2m, BETA-2-MICROGLOBULIN, mCG_11606, RP23-34E24.5-001
expression_system_common: Fall armyworm
expression_system_strain: SF9
expression_system_vector_type: BACULOVIRUS TRANSFER VECTOR
expression_system_plasmid: PBACPHP10
Authors : Zajonc, D.M.
Keywords : GAMMA DELTA T CELLS, GLYCOLIPID PRESENTATION, MHC, CD1, CELL MEMBRANE, ENDOSOME, GLYCOPROTEIN, IMMUNE RESPONSE, IMMUNOGLOBULIN DOMAIN, INNATE IMMUNITY, LYSOSOME, MEMBRANE, TRANSMEMBRANE, MHC I, SECRETED, IMMUNE SYSTEM, Disulfide bond, Immunity
Exp. method : X-RAY DIFFRACTION ( 2.29 Å )
Citation :

Cardiolipin Binds to CD1d and Stimulates CD1d-Restricted {gamma}{delta} T Cells in the Normal Murine Repertoire.

Dieude, M.,Striegl, H.,Tyznik, A.J.  et al.
(2011)  J.Immunol.  186 : 4771 - 4781

PubMed: 21389252
DOI: 10.4049/jimmunol.1000921

Reaction

Chain : C, A
UniProt : P11609 (CD1D1_MOUSE)
Reaction : -
Chain : D, B
UniProt : Q91XJ8 (B2MG_MOUSE)
Reaction : -