Code : |
3M3Y
PDBj
RCSB PDB
PDBe
|
Title : |
RNA polymerase II elongation complex C |
Release Data : |
2010-05-12 |
Compound : |
mol_id |
molecule |
chains |
synonym
|
1 |
DNA-directed RNA polymerase II subunit RPB1
|
A
|
RNA polymerase II subunit B1, RNA polymerase II subunit 1, DNA-directed RNA polymerase III largest subunit, RNA polymerase II subunit B220
|
|
ec: 2.7.7.6
|
mol_id |
molecule |
chains |
synonym
|
2 |
DNA-directed RNA polymerase II subunit RPB2
|
B
|
RNA polymerase II subunit 2, DNA-directed RNA polymerase II 140 kDa polypeptide, B150
|
|
ec: 2.7.7.6
|
mol_id |
molecule |
chains |
synonym
|
3 |
DNA-directed RNA polymerase II subunit RPB3
|
C
|
RNA polymerase II subunit B3, RNA polymerase II subunit 3, DNA-directed RNA polymerase II 45 kDa polypeptide, B44.5
|
mol_id |
molecule |
chains |
synonym
|
4 |
DNA-directed RNA polymerases I, II, and III subunit RPABC1
|
E
|
RNA polymerases I, II, and III subunit ABC1, DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide, ABC27
|
mol_id |
molecule |
chains |
synonym
|
5 |
DNA-directed RNA polymerases I, II, and III subunit RPABC2
|
F
|
RNA polymerases I, II, and III subunit ABC2, DNA-directed RNA polymerases I, II, and III 23 kDa polypeptide, ABC23
|
mol_id |
molecule |
chains |
synonym
|
6 |
DNA-directed RNA polymerases I, II, and III subunit RPABC3
|
H
|
RNA polymerases I, II, and III subunit ABC3, DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptide, ABC14.5, ABC14.4
|
mol_id |
molecule |
chains |
synonym
|
7 |
DNA-directed RNA polymerase II subunit RPB9
|
I
|
RNA polymerase II subunit B9, DNA-directed RNA polymerase II subunit 9, DNA-directed RNA polymerase II 14.2 kDa polypeptide, B12.6
|
mol_id |
molecule |
chains |
synonym
|
8 |
DNA-directed RNA polymerases I, II, and III subunit RPABC5
|
J
|
RNA polymerases I, II, and III subunit ABC5, DNA-directed RNA polymerases I, II, and III 8.3 kDa polypeptide, ABC10-beta, ABC8
|
mol_id |
molecule |
chains |
synonym
|
9 |
DNA-directed RNA polymerase II subunit RPB11
|
K
|
RNA polymerase II subunit B11, DNA-directed RNA polymerase II 13.6 kDa polypeptide, B13.6
|
mol_id |
molecule |
chains |
synonym
|
10 |
DNA-directed RNA polymerases I, II, and III subunit RPABC4
|
L
|
RNA polymerases I, II, and III subunit ABC4, ABC10-alpha
|
mol_id |
molecule |
chains |
|
11 |
RNA (5'-R(*AP*UP*GP*GP*AP*GP*AP*GP*GP*AP*C)-3')
|
R
|
|
mol_id |
molecule |
chains |
|
12 |
DNA (28-MER)
|
T
|
|
mol_id |
molecule |
chains |
|
13 |
DNA (5'-D(*GP*TP*GP*GP*TP*TP*AP*TP*GP*GP*GP*TP*AP*G)-3')
|
N
|
|
|
Source : |
mol_id |
organism_scientific |
organism_common
|
|
1 |
Saccharomyces cerevisiae
(taxid:4932)
|
Brewer's yeast,lager beer yeast,yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
2 |
Saccharomyces cerevisiae
(taxid:4932)
|
Brewer's yeast,lager beer yeast,yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
3 |
Saccharomyces cerevisiae
(taxid:4932)
|
Brewer's yeast,lager beer yeast,yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
4 |
Saccharomyces cerevisiae
(taxid:4932)
|
Brewer's yeast,lager beer yeast,yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
5 |
Saccharomyces cerevisiae
(taxid:4932)
|
Brewer's yeast,lager beer yeast,yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
6 |
Saccharomyces cerevisiae
(taxid:4932)
|
Brewer's yeast,lager beer yeast,yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
7 |
Saccharomyces cerevisiae
(taxid:4932)
|
Brewer's yeast,lager beer yeast,yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
8 |
Saccharomyces cerevisiae
(taxid:4932)
|
Brewer's yeast,lager beer yeast,yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
9 |
Saccharomyces cerevisiae
(taxid:4932)
|
Brewer's yeast,lager beer yeast,yeast
|
|
mol_id |
organism_scientific |
organism_common
|
|
10 |
Saccharomyces cerevisiae
(taxid:4932)
|
Brewer's yeast,lager beer yeast,yeast
|
|
mol_id |
organism_scientific |
|
|
11 |
|
|
|
|
synthetic: yes
|
mol_id |
organism_scientific |
|
|
12 |
|
|
|
|
synthetic: yes
|
mol_id |
organism_scientific |
|
|
13 |
|
|
|
|
synthetic: yes
|
|
Authors : |
Wang, D., Zhu, G., Huang, X., Lippard, S.J. |
Keywords : |
TRANSCRIPTION, MRNA, MULTIPROTEIN COMPLEX, MOLECULAR MACHINE, DNA, DNA Damage, Cancer, Platinum Drug, DNA-binding, DNA-directed RNA polymerase, Isopeptide bond, Magnesium, Metal-binding, Nucleotidyltransferase, Nucleus, Phosphoprotein, Transferase, Ubl conjugation, Zinc, Zinc-finger, Polymorphism, Cytoplasm, DNA repair, TRANSFERASE-DNA-RNA HYBRID complex |
Exp. method : |
X-RAY DIFFRACTION ( 3.18 Å ) |
Citation : |
X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct.
Wang, D.,Zhu, G.,Huang, X.
et al.
(2010)
Proc.Natl.Acad.Sci.USA
107
: 9584
- 9589
PubMed: 20448203
DOI: 10.1073/pnas.1002565107
|