Het-PDB Navi2 (PDB: 3LTQ)

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Ligands
Code	Name	Link
ACT	Acetate ion	PoSSuM
SO4	Sulfate ion	PoSSuM
TB	Terbium(III) ion	PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 3LTQ

Code :

3LTQ PDBj RCSB PDB PDBe

Header :

CYTOKINE

Title :

Structure of Interleukin 1B solved by SAD using an inserted Lanthanide Binding Tag

Release Data :

2011-02-16

Compound :

mol_id	molecule	chains	synonym
1	Interleukin-1 beta	A	IL-1 beta, Catabolin
	fragment: sequence database residues 117-269

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:469008)
	gene: IL1B, IL1F2 expression_system_strain: BL21(DE3) expression_system_vector_type: plasmid expression_system_plasmid: pET3a

Authors :

Peisach, E., Allen, K.N.

Keywords :

Lanthanide Binding Tag, LBT, terbium, IL1B, Cytokine, Inflammatory response, Mitogen, Pyrogen, Secreted

Exp. method :

X-RAY DIFFRACTION ( 2.100 Å )

Citation :

Engineering encodable lanthanide-binding tags into loop regions of proteins.

Barthelmes, K.,Reynolds, A.M.,Peisach, E. et al.
(2011) J.Am.Chem.Soc. 133 : 808 - 819

Double-Lanthanide-Binding Tags for Macromolecular Crystallographic Structure Determination

Silvaggi, N.R.,Martin, L.J.,Schwalbe, H. et al.
(2007) J.Am.Chem.Soc. 129 : 7114 - 7120

PDB ID: 3LTQ