Het-PDB Navi2 (PDB: 3LGG)

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Ligands
Code	Name		Style	Show	Link
CFE	(8r)-3-beta-D-ribofuranosyl-3,6,7,8-tetrahydroimidazo[4,5-D][1,3]diazepin-8-ol				PoSSuM
ZN	Zinc ion				PoSSuM

Non-standard Residues
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Glycosylation
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NAG	2-acetamido-2-deoxy-beta-D-glucopyranose

Modification
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Download interaction data: 3LGG

Code :

3LGG PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

Crystal structure of human adenosine deaminase growth factor, adenosine deaminase type 2 (ADA2) complexed with transition state analogue, coformycin

Release Data :

2010-02-09

Compound :

mol_id	molecule	chains	synonym
1	Adenosine deaminase CECR1	A,B	Cat eye syndrome critical region protein 1
	ec: 3.5.4.4

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Drosophila (taxid:7215)
	gene: ADA2, CECR1, IDGFL expression_system_vector_type: pRMHa3, pS2neo expression_system_plasmid: pRMHa3-ADA2

Authors :

Zavialov, A.V.

Keywords :

TIM barrel, dimerization and receptor binding domains, Glycoprotein, Hydrolase, Growth Factor, Secreted

Exp. method :

X-RAY DIFFRACTION ( 2.50 Å )

Citation :

Structural basis for the growth factor activity of human adenosine deaminase ADA2.

Zavialov, A.V.,Yu, X.,Spillmann, D. et al.
(2010) J.Biol.Chem. 285 : 12367 - 12377

Chain :

A, B

UniProt :

Q9NZK5 (ADA2_HUMAN)

PDB ID: 3LGG