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Ligands
Code Name Style Show Link
SO4 Sulfate ion
CL Chloride ion
C2G [cytidine-5'-phosphate] glycerylphosphoric acid ester
EDO 1,2-ethanediol
Non-standard Residues
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Glycosylation
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Code : 3L7L   PDBj   RCSB PDB   PDBe
Header : STRUCTURAL PROTEIN
Title : Structure of the Wall Teichoic Acid Polymerase TagF, H444N + CDPG (30 minute soak)
Release Data : 2010-04-28
Compound :
mol_id molecule chains
1 Teichoic acid biosynthesis protein F A,B,C,D
fragment: TagF
mutation: H444N
Source :
mol_id organism_scientific expression_system
1 Staphylococcus epidermidis  (taxid:176279) Escherichia coli  (taxid:562)
strain: RP62A
gene: SERP1960, tagF
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pET28b
Authors : Lovering, A.L., Strynadka, N.C.J.
Keywords : GT-B fold, monotopic membrane protein, STRUCTURAL PROTEIN
Exp. method : X-RAY DIFFRACTION ( 2.950 Å )
Citation :

Structure of the bacterial teichoic acid polymerase TagF provides insights into membrane association and catalysis.

Lovering, A.L.,Lin, L.Y.,Sewell, E.W.  et al.
(2010)  Nat.Struct.Mol.Biol.  17 : 582 - 589

PubMed: 20400947
DOI: 10.1038/nsmb.1819

Chain : A, B, C, D
UniProt : Q5HLM5 (TAGF_STAEQ)
Reaction: EC: Evidence:
Physiological Direction:
4-O-[(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl- (1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CDP-glycerol = 4-O-{[(2R)-1-glycerylphospho](n)-(2R)- 1-glycerylphospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl- alpha-D-glucosaminyl undecaprenyl diphosphate + n CMP + n H(+) 2.7.8.12 PubMed:20400947
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