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Ligands
Code Name Style Show Link
CLR Cholesterol
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
BMA Beta-D-mannopyranose
MAN Alpha-D-mannopyranose
NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
Modification
Code Name Show
Code : 3JD8   PDBj   RCSB PDB   PDBe
Header : MEMBRANE PROTEIN
Title : cryo-EM structure of the full-length human NPC1 at 4.4 angstrom
Release Data : 2016-06-01
Compound :
mol_id molecule chains
1 Niemann-Pick C1 protein A
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Homo sapiens  (taxid:9606)
gene: NPC1
expression_system_common: Human
expression_system_cell_line: HEK-293F
expression_system_plasmid: pCAG
Authors : Gong, X., Qian, H.W., Zhou, X.H., Wu, J.P., Zhou, Q., Yan, N.
Keywords : membrane protein
Exp. method : ELECTRON MICROSCOPY ( 4.43 Å )
Citation :

The structure of Niemann-Pick C1 protein

Gong, X.,Qiang, H.W.,Zhou, X.H.  et al.
To Be Published 

Chain : A
UniProt : O15118 (NPC1_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
cholesterol(in) = cholesterol(out) - PubMed:18772377
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