PDB ID: 3IMT
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Structure summary
Code : | 3IMT PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HORMONE | ||||||||||||
Title : | Transthyretin in complex with (E)-4-(4-aminostyryl)-2,6-dibromophenol | ||||||||||||
Release Data : | 2010-01-12 | ||||||||||||
Compound : |
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Source : |
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Authors : | Connelly, S., Wilson, I. | ||||||||||||
Keywords : | Hormone, Growth Factor, Amyloid, Disease mutation, Gamma-carboxyglutamic acid, Glycoprotein, Polymorphism, Polyneuropathy, Retinol-binding, Secreted, Thyroid hormone, Transport, Vitamin A | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.400 Å ) | ||||||||||||
Citation : |
A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
Choi, S.,Reixach, N.,Connelly, S.
et al.
PubMed: 20043671 |
Reaction
Chain : | A, B |
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UniProt : | P02766 (TTHY_HUMAN) |
Reaction : | - |