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Ligands
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FK5 8-deethyl-8-[but-3-enyl]-ascomycin
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Glycosylation
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Code : 3IHZ   PDBj   RCSB PDB   PDBe
Header : ISOMERASE
Title : Crystal structure of the FK506 binding domain of Plasmodium vivax FKBP35 in complex with FK506
Release Data : 2010-06-16
Compound :
mol_id molecule chains
1 70 kDa peptidylprolyl isomerase, putative A,B
fragment: FK506-binding domain, residues 1-126
Source :
mol_id organism_scientific expression_system
1 Plasmodium vivax  (taxid:5855) Escherichia coli  (taxid:469008)
strain: Salvador I
expression_system_strain: BL21(DE3)
expression_system_vector_type: Plasmid
expression_system_plasmid: pSUMO
Authors : Qureshi, I.A., Alag, R., Yoon, H.S., Lescar, J.
Keywords : Plasmodium vivax, FKBP35, FK506, Isomerase
Exp. method : X-RAY DIFFRACTION ( 1.67 Å )
Citation :

NMR and crystallographic structures of the FK506 binding domain of human malarial parasite Plasmodium vivax FKBP35

Alag, R.,Qureshi, I.A.,Bharatham, N.  et al.
(2010)  Protein Sci.  19 : 1577 - 1586

PubMed: 20572013
DOI: 10.1002/pro.438

Chain : A, B
UniProt : A5K8X6 (A5K8X6_PLAVS)
Reaction: EC: Evidence:
Physiological Direction:
[protein]-peptidylproline (omega=180) = [protein]- peptidylproline (omega=0) 5.2.1.8 PROSITE- ProRule:PRU00277
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