Brand  (β version)

PDB ID: 3HZT

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Ligands
Code Name Style Show Link
GOL Glycerol PoSSuM
J60 5-[(E)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-N-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide PoSSuM
MG Magnesium ion PoSSuM
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Structure summary

Code : 3HZT   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal structure of Toxoplasma gondii CDPK3, TGME49_105860
Release Data : 2009-07-21
Compound :
mol_id molecule chains
1 Calcium-dependent protein kinase 3 A
ec: 2.7.11.17
fragment: UNP residues 72-537
Source :
mol_id organism_scientific expression_system
1 Toxoplasma gondii  (taxid:508771) Escherichia coli  (taxid:562)
strain: ME49
gene: TGME49_105860
expression_system_vector_type: plasmid
expression_system_plasmid: pET15_mhl
Authors : Wernimont, A.K., Artz, J.D., Finnerty, P., Wasney, G., Allali-Hassani, A., Vedadi, M., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Amani, M., Structural Genomics Consortium (SGC)
Keywords : calcium dependent kinase, calmodulin, troponin parasite, Structural Genomics, Structural Genomics Consortium, SGC, ATP-binding, Kinase, Nucleotide-binding, Serine/threonine-protein kinase, Transferase
Exp. method : X-RAY DIFFRACTION ( 2.000 Å )
Citation :

Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium.

Wernimont, A.K.,Artz, J.D.,Finerty, P.  et al.
(2010)  Nat.Struct.Mol.Biol.  17 : 596 - 601

PubMed: 20436473
DOI: 10.1038/nsmb.1795

Reaction

Chain : A
UniProt : B6KR85 (Q3HNM6_TOXGO)
Reaction : -