Het-PDB Navi2 (PDB: 3HIW)

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Ligands
Code	Name		Style	Show	Link
C2X	9,9'-{(2r,3r,3ar,5s,7ar,9r,10r,10ar,12s,23r,25ar,27r,28r,28ar,30s,32ar,35ar,37s,39ar)-9-(6-amino-9h-purin-9-yl)-34-[(4-amino-5h-pyrrolo[3,2-D]pyrimidin-7-yl)methyl]-5,12,23,30,37-pentahydroxy-3,10,28-trimethoxy-5,12,23,30,37-pentaoxidotetracosahydro-2h,7h,25h-trifuro[3,2-f:3',2'-L:3'',2''-x]pyrrolo[3,4-R][1,3,5,9,11,15,17,21,23,27,29,2,4,10,16,22,28]undecaoxazapentaphosphacyclopentatriacontine-2,27-diyl}bis(2-amino-3,9-dihydro-6h-purin-6-one)				PoSSuM

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Download interaction data: 3HIW

Code :

3HIW PDBj RCSB PDB PDBe

Header :

Hydrolase/Hydrolase inhibitor

Title :

Crystal structure of Saporin-L1 in complex with the cyclic tetranucleotide inhibitor, a transition state analogue

Release Data :

2009-12-08

Compound :

mol_id	molecule	chains
1	Vacuolar saporin	A,B

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Saponaria officinalis (taxid:3572)	Common soapwort	Escherichia coli (taxid:562)

Authors :

Ho, M., Sturm, M.B., Almo, S.C., Schramm, V.L.

Keywords :

transition state, ribosome inactivating proteins, RIPs, Hydrolase, Plant defense, Protein synthesis inhibitor, Toxin, Hydrolase-Hydrolase inhibitor COMPLEX

Exp. method :

X-RAY DIFFRACTION ( 1.800 Å )

Citation :

Transition state analogues in structures of ricin and saporin ribosome-inactivating proteins.

Ho, M.C.,Sturm, M.B.,Almo, S.C. et al.
(2009) Proc.Natl.Acad.Sci.USA 106 : 20276 - 20281

PubMed: 19920175
DOI: 10.1073/pnas.0911606106

PDB ID: 3HIW

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