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Ligands
Code Name Style Show Link
NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
Non-standard Residues
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HZP (4s)-4-hydroxy-L-proline
Glycosylation
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Code : 3GXE   PDBj   RCSB PDB   PDBe
Header : CELL ADHESION
Title : Complex of a Low Affinity Collagen Site with the Fibronectin 8-9FnI Domain Pair
Release Data : 2010-04-07
Compound :
mol_id molecule chains synonym
1 Fibronectin B,A FN, Cold-insoluble globulin, CIG, Ugl-Y1, Ugl-Y2, Ugl-Y3
fragment: 8-9FnI, UNP residues 516-608
mutation: N528Q, R534K
mol_id molecule chains synonym
2 Collagen alpha-1(I) chain F Alpha-1 type I collagen
fragment: ColI.260, UNP residues 254-275
mol_id molecule chains synonym
3 Collagen alpha-1(I) chain E Alpha-1 type I collagen
fragment: ColI.260, UNP residues 254-275
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Pichia pastoris  (taxid:4922)
gene: FN
expression_system_strain: X-33
expression_system_vector_type: Genomic integration
mol_id organism_scientific
2
synthetic: yes
other_details: Standard peptide synthesis
mol_id organism_scientific
3
synthetic: yes
other_details: Standard peptide synthesis
Authors : Sladek, B., Campbell, I.D., Vakonakis, I.
Keywords : protein-peptide complex, CELL ADHESION
Exp. method : X-RAY DIFFRACTION ( 2.600 Å )
Citation :

Structural analysis of collagen type I interactions with human fibronectin reveals a cooperative binding mode

Erat, M.C.,Sladek, B.,Campbell, I.D.  et al.
(2013)  J.Biol.Chem.  288 : 17441 - 17450

PubMed: 23653354
DOI: 10.1074/jbc.M113.469841

Chain : B, A
UniProt : P02751 (FINC_HUMAN)
Reaction : -
Chain : E
UniProt : P02452 (CO1A1_HUMAN)
Reaction : -