Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
CAQ Catechol
CL Chloride ion
FE Fe (III) ion
GOL Glycerol
NA Sodium ion
Code : 3FW4
Header : TRANSPORT PROTEIN
Title : Crystal structure of Siderocalin (NGAL, Lipocalin 2) complexed with Ferric Catechol
Release Data : 2010-05-05
Compound :
mol_id molecule chains synonym
1 Neutrophil gelatinase-associated lipocalin A,B,C NGAL, p25, 25 kDa alpha-2-microglobulin-related subunit of MMP-9, Lipocalin-2, Oncogene 24p3
mutation: C87S
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: HNL, LCN2, NGAL
expression_system_strain: BL21(DE3)+RIL
expression_system_vector_type: Plasmid
expression_system_plasmid: pGEX-4T3
Authors : Clifton, M.C., Strong, R.K.
Keywords : 8-stranded anti-parallel beta barrel, 310-helix, Glycoprotein, Pyrrolidone carboxylic acid, Secreted, TRANSPORT PROTEIN
Exp. method : X-RAY DIFFRACTION ( 2.30 Å )
Citation :

Iron traffics in circulation bound to a siderocalin (Ngal)-catechol complex.

Bao, G.,Clifton, M.,Hoette, T.M.  et al.
(2010)  Nat.Chem.Biol.  6 : 602 - 609

PubMed: 20581821
DOI: 10.1038/nchembio.402

Chain : A, B, C
UniProt : P80188 (NGAL_HUMAN)
Reaction : -