Het-PDB Navi2 (PDB: 3FW4)

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Ligands
Code	Name	Link
FE	Fe (III) ion	PoSSuM
CAQ	Catechol	PoSSuM
NA	Sodium ion	PoSSuM
CL	Chloride ion	PoSSuM
GOL	Glycerol	PoSSuM

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Download interaction data: 3FW4

Code :

3FW4 PDBj RCSB PDB PDBe

Header :

TRANSPORT PROTEIN

Title :

Crystal structure of Siderocalin (NGAL, Lipocalin 2) complexed with Ferric Catechol

Release Data :

2010-05-05

Compound :

mol_id	molecule	chains	synonym
1	Neutrophil gelatinase-associated lipocalin	A,B,C	NGAL, p25, 25 kDa alpha-2-microglobulin-related subunit of MMP-9, Lipocalin-2, Oncogene 24p3
	mutation: C87S

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: HNL, LCN2, NGAL expression_system_strain: BL21(DE3)+RIL expression_system_vector_type: Plasmid expression_system_plasmid: pGEX-4T3

Authors :

Clifton, M.C., Strong, R.K.

Keywords :

8-stranded anti-parallel beta barrel, 310-helix, Glycoprotein, Pyrrolidone carboxylic acid, Secreted, TRANSPORT PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 2.30 Å )

Citation :

Iron traffics in circulation bound to a siderocalin (Ngal)-catechol complex.

Bao, G.,Clifton, M.,Hoette, T.M. et al.
(2010) Nat.Chem.Biol. 6 : 602 - 609

PDB ID: 3FW4