Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
JPL 5-(cyclohexylmethyl)-2-(2,4-dichlorophenoxy)phenol
NAD Nicotinamide-adenine-dinucleotide
Code : 3FNG
Header : OXIDOREDUCTASE
Title : Crystal structure of InhA bound to triclosan derivative
Release Data : 2009-01-20
Compound :
mol_id molecule chains synonym
1 Enoyl-[acyl-carrier-protein] reductase [NADH] A NADH-dependent enoyl-ACP reductase
ec: 1.3.1.9
Source :
mol_id organism_scientific expression_system
1 Mycobacterium tuberculosis  (taxid:1773) Escherichia coli  (taxid:562)
gene: inhA, Rv1484, MT1531, MTCY277.05
Authors : Wang, F.
Keywords : InhA, triclosan, tuberculosis, Antibiotic resistance, Fatty acid biosynthesis, Lipid synthesis, NAD, Oxidoreductase
Exp. method : X-RAY DIFFRACTION ( 1.97 Å )
Citation :

Triclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis.

Freundlich, J.S.,Wang, F.,Vilcheze, C.  et al.
(2009)  Chemmedchem  4 : 241 - 248

PubMed: 19130456
DOI: 10.1002/cmdc.200800261

Chain : A
UniProt : P0A5Y6 (multiple entry names are found)
Reaction : -