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Ligands
Code Name Style Show Link
2T1 2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid
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Code : 3FMZ   PDBj   RCSB PDB   PDBe
Header : TRANSPORT PROTEIN
Title : Crystal Structure of Retinol-Binding Protein 4 (RBP4) in complex with non-retinoid ligand
Release Data : 2009-01-27
Compound :
mol_id molecule chains synonym
1 Retinol-binding protein 4 A,B Plasma retinol-binding protein, PRBP, RBP
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: RBP4, PRO2222
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pET21a
Authors : Wang, Z., Johnstone, S., Walker, N.P.
Keywords : retinol binding, Disease mutation, Retinol-binding, Secreted, Sensory transduction, Transport, Vision, Vitamin A, TRANSPORT PROTEIN
Exp. method : X-RAY DIFFRACTION ( 2.900 Å )
Citation :

Identification and Characterization of a Non-retinoid Ligand for Retinol-binding Protein 4 Which Lowers Serum Retinol-binding Protein 4 Levels in Vivo.

Motani, A.,Wang, Z.,Conn, M.  et al.
(2009)  J.Biol.Chem.  284 : 7673 - 7680

PubMed: 19147488
DOI: 10.1074/jbc.M809654200

Chain : A, B
UniProt : P02753 (RET4_HUMAN)
Reaction : -