Het-PDB Navi2 (PDB: 3FMQ)

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Ligands
Code	Name	Link
FE	Fe (III) ion	PoSSuM
FUG	Fumagillin	PoSSuM
SO4	Sulfate ion	PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 3FMQ

Code :

3FMQ PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

Crystal structure of an Encephalitozoon cuniculi methionine aminopeptidase type 2 with angiogenesis inhibitor fumagillin bound

Release Data :

2009-01-13

Compound :

mol_id	molecule	chains	synonym
1	Methionine aminopeptidase 2	A,B	MetAP 2, MAP-2, Peptidase M 2
	ec: 3.4.11.18

Source :

mol_id	organism_scientific	expression_system
1	Encephalitozoon cuniculi (taxid:6035)	Spodoptera frugiperda (taxid:7108)
	strain: GB-M1 gene: ECU10_0750, MAP2 expression_system_common: Fall armyworm expression_system_cell_line: SF9 expression_system_vector_type: Baculovirus expression_system_plasmid: pBAC2

Authors :

Alvarado, J.J., Russell, M., Zhang, A., Adams, J., Toro, R., Burley, S.K., Weiss, L.M., Almo, S.C., New York SGX Research Center for Structural Genomics (NYSGXRC)

Keywords :

METHIONINE AMINOPEPTIDASE TYPE2, METAP2, METAP2 FUMAGILLIN COMPLEX, ENCEPHALITOZOON CUNICULI, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, New York SGX Research Center for Structural Genomics, NYSGXRC, Aminopeptidase, Cobalt, Hydrolase, Metal-binding, Protease

Exp. method :

X-RAY DIFFRACTION ( 2.50 Å )

Citation :

Structure of a microsporidian methionine aminopeptidase type 2 complexed with fumagillin and TNP-470.

Alvarado, J.J.,Nemkal, A.,Sauder, J.M. et al.
(2009) Mol.Biochem.Parasitol. 168 : 158 - 167

PubMed: 19660503
DOI: 10.1016/j.molbiopara.2009.07.008

PDB ID: 3FMQ

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