PDB ID: 3FI2
Hetero Atom Contents
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Color scheme of protein:
Code | Name | Style | Show | Link | |
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EDO | 1,2-ethanediol | PoSSuM | |||
JK1 | 3-{4-[(phenylcarbamoyl)amino]-1h-pyrazol-1-yl}-N-(3,4,5-trimethoxyphenyl)benzamide | PoSSuM |
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OCY | Hydroxyethylcysteine |
Code | Name | Emphasize |
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Download interaction data: 3FI2
Structure summary
Code : | 3FI2 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | Crystal structure of JNK3 with amino-pyrazole inhibitor, SR-3451 | ||||||||||||
Release Data : | 2009-03-03 | ||||||||||||
Compound : |
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Source : |
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Authors : | Habel, J.E. | ||||||||||||
Keywords : | JNK3, protein-inhibitor complex, Alternative splicing, ATP-binding, Chromosomal rearrangement, Cytoplasm, Epilepsy, Kinase, Nucleotide-binding, Phosphoprotein, Serine/threonine-protein kinase, Transferase | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.28 Å ) | ||||||||||||
Citation : |
Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38.
Kamenecka, T.,Habel, J.,Duckett, D.
et al.
PubMed: 19261605 |
Reaction
Chain : | A | ||||||||||||
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UniProt : | P53779 (MK10_HUMAN) | ||||||||||||
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