Brand  (β version)

color scheme of protein:

hetatm:

chain: Hide other chain(s)

Code Name Link
CL Chloride ion
MG Magnesium ion
PI Hydrogenphosphate ion
ADP Adenosine-5'-diphosphate
Code : 3ETJ
Header : lyase
Title : crystal structure E. coli purk in complex with Mg, ADP, and pi
Release Data : 2008-10-21
Compound :
mol_id 1
molecule phosphoribosylaminoimidazole carboxylase atpase subunit
chain A, B
synonym air carboxylase, airc
ec 4.1.1.21
engineered yes
mutation yes
Source :
mol_id 1
organism_scientific Escherichia coli
organism_taxid 83333
strain k12
gene b0522, jw0511, purk, purk_ecoli
expression_system Escherichia coli
expression_system_taxid 562
expression_system_strain hms174(de3)
expression_system_vector_type plasmid
expression_system_plasmid pet31
Authors : H.M.Holden, J.B.Thoden
Keywords : atp-grasp, purine biosynthesis, antimicrobial, atp-binding, decarboxylase, lyase, nucleotide-binding
Exp. method : X-ray diffraction ( 1.6 Å )
Chain : A, B
UniProt : P09029 (PURK_ECOLI)
Reaction : ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole + HCO(3)(-) = ADP + phosphate + 5-carboxyamino-1-(5-phospho-D- ribosyl)imidazole.