PDB ID: 3EM4
Hetero Atom Contents
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Color scheme of protein:
Code | Name | Style | Show | Link | |
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DR7 | (3s,8s,9s,12s)-3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-2,5, 6,10,13-pentaazatetradecanedioic acid dimethyl ester | PoSSuM | |||
PO4 | Phosphate ion | PoSSuM |
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Download interaction data: 3EM4
Structure summary
Code : | 3EM4 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | Crystal structure of atazanavir (ATV) in complex with I50L/A71V drug-resistant HIV-1 protease | ||||||||||||
Release Data : | 2009-09-01 | ||||||||||||
Compound : |
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Authors : | Prabu-Jeyabalan, M., King, N., Royer, C., Schiffer, C. | ||||||||||||
Keywords : | drug resistance, hypersusceptibility, protease inhibitor, hiv, atazanavir, AIDS, Hydrolase, Protease | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.100 Å ) | ||||||||||||
Citation : |
Kinetic and Structural studies on atazanavir-specific I50L drug-resistant HIV-1 protease mutant
Prabu-Jeyabalan, M.,King, N.,Bandaranayake, R.
et al.
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Reaction
Chain : | A, B, U, V | ||||||||||||||||||||||||
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UniProt : | P03369 (POL_HV1A2) | ||||||||||||||||||||||||
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