Het-PDB Navi2 (PDB: 3EKU)

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Ligands
Code	Name	Link
ATP	Adenosine-5'-triphosphate	PoSSuM
CA	Calcium ion	PoSSuM
CY9	(3s,3ar,4s,6s,6ar,7e,10s,12r,13e,15r,15ar)-3-benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylidene-1,11-dioxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1h-cycloundeca[D]isoindol-15-yl acetate	PoSSuM

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Download interaction data: 3EKU

Code :

3EKU PDBj RCSB PDB PDBe

Header :

CONTRACTILE PROTEIN

Title :

Crystal Structure of Monomeric Actin bound to Cytochalasin D

Release Data :

2008-10-07

Compound :

mol_id	molecule	chains
1	Actin-5C	A
	mutation: A204E, P243K

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Drosophila melanogaster (taxid:7227)	Fruit fly	Spodoptera frugiperda (taxid:7108)
	gene: Act5C, CG4027 expression_system_common: Fall armyworm expression_system_strain: SF9 expression_system_vector_type: Baculovirus

Authors :

Nair, U.B., Joel, P.B., Wan, Q., Lowey, S., Rould, M.A., Trybus, K.M.

Keywords :

Motor protein, ATP-state, fungal toxin, Acetylation, ATP-binding, Cytoplasm, Cytoskeleton, Nucleotide-binding, CONTRACTILE PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 2.500 Å )

Citation :

Crystal structures of monomeric actin bound to cytochalasin D.

Nair, U.B.,Joel, P.B.,Wan, Q. et al.
(2008) J.Mol.Biol. 384 : 848 - 864

Crystal Structures of Expressed Non-polymerizable Monomeric Actin in the ADP and ATP states

Rould, M.A.,Wan, Q.,Joel, P.B. et al.
(2006) J.Biol.Chem. 281 : 31909 - 31919

Chain :

UniProt :

P10987 (ACT1_DROME)

PDB ID: 3EKU