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Ligands
Code Name Style Show Link
CTC 7-chlorotetracycline
MG Magnesium ion
Non-standard Residues
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MSE Selenomethionine
Glycosylation
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Code : 3EGZ   PDBj   RCSB PDB   PDBe
Header : RNA
Title : Crystal structure of an in vitro evolved tetracycline aptamer and artificial riboswitch
Release Data : 2008-10-28
Compound :
mol_id molecule chains synonym
1 U1 small nuclear ribonucleoprotein A A U1 snRNP protein A, U1A protein, U1-A
mol_id molecule chains
2 Tetracycline aptamer and artificial riboswitch B
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: SNRPA
expression_system_vector_type: plasmid
expression_system_plasmid: pET
mol_id organism_scientific
2
synthetic: yes
other_details: In vitro evolved aptamer
Authors : Xiao, H., Edwards, T.E., Ferre-D'Amare, A.R.
Keywords : tetracycline, aptamer, riboswitch, antibiotic, RNA
Exp. method : X-RAY DIFFRACTION ( 2.200 Å )
Citation :

Structural basis for specific, high-affinity tetracycline binding by an in vitro evolved aptamer and artificial riboswitch

Xiao, H.,Edwards, T.E.,Ferre-D'Amare, A.R.
(2008)  Chem.Biol.  15 : 1125 - 1137

PubMed: 18940672
DOI: 10.1016/j.chembiol.2008.09.004

Chain : A
UniProt : P09012 (SNRPA_HUMAN)
Reaction : -