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Ligands
Code Name Style Show Link
0PA Cyclopentylacetic acid
ACT Acetate ion
Non-standard Residues
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Code : 3DWR   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Leishmania major coproporphyrinogen III oxidase with bound ligand
Release Data : 2008-09-09
Compound :
mol_id molecule chains synonym
1 Coproporphyrinogen III oxidase A,B Coproporphyrinogenase, Coprogen oxidase
ec: 1.3.3.3
Source :
mol_id organism_scientific expression_system
1 Leishmania major  (taxid:5664) Escherichia coli  (taxid:562)
strain: Friedlin
gene: LMAJ006828, LmjF06.1270
expression_system_strain: BL21
expression_system_vector_type: plasmid
expression_system_plasmid: pET14b, BG1861
Authors : Le Trong, I., Merritt, E.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Keywords : fragment cocktail, Structural Genomics, Structural Genomics of Pathogenic Protozoa Consortium, SGPP, Heme biosynthesis, Oxidoreductase, Porphyrin biosynthesis
Exp. method : X-RAY DIFFRACTION ( 1.66 Å )
Citation :

Leishmania major coproporphyrinogen III oxidase with bound ligand

Merritt, E.A.,Le Trong, I.,Larson, E.T.  et al.
To be Published 

Chain : A, B
UniProt : P84155 (HEM6_LEIMA)
Reaction: EC: Evidence:
Physiological Direction:
coproporphyrinogen III + 2 H(+) + O2 = 2 CO2 + 2 H2O + protoporphyrinogen IX 1.3.3.3 ECO:0000305
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