Het-PDB Navi2 (PDB: 3DH3)

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Ligands
Code	Name		Style	Show	Link

Non-standard Residues
Code	Name	Show
FHU	(5s,6r)-5-fluoro-6-hydroxy-pseudouridine-5'-monophosphate

Glycosylation
Code	Name	Emphasize

Modification
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Download interaction data: 3DH3

Code :

3DH3 PDBj RCSB PDB PDBe

Header :

ISOMERASE/RNA

Title :

Crystal Structure of RluF in complex with a 22 nucleotide RNA substrate

Release Data :

2009-04-28

Compound :

mol_id	molecule	chains	synonym
1	Ribosomal large subunit pseudouridine synthase F	A,B,C,D	rRNA-uridine isomerase F, rRNA pseudouridylate synthase F
	ec: 5.4.99.-

mol_id	molecule	chains
2	stem loop fragment of E. Coli 23S RNA	E,F,G,H

Source :

mol_id	organism_scientific	expression_system
1	Escherichia coli (taxid:562)	Escherichia coli (taxid:562)
	gene: rluF, yjbC, b4022, JW3982 expression_system_strain: BL21(DE3) expression_system_vector_type: plasmid expression_system_plasmid: pET30b

mol_id	organism_scientific
2
	synthetic: yes

Authors :

Alian, A., DeGiovanni, A., Stroud, R.M., Finer-Moore, J.S.

Keywords :

protein-rna complex, S4 domain, alpha/beta protein, Isomerase, RNA-binding, rRNA processing, ISOMERASE-RNA COMPLEX

Exp. method :

X-RAY DIFFRACTION ( 3.00 Å )

Citation :

Crystal structure of an RluF-RNA complex: a base-pair rearrangement is the key to selectivity of RluF for U2604 of the ribosome.

Alian, A.,DeGiovanni, A.,Griner, S.L. et al.
(2009) J.Mol.Biol. 388 : 785 - 800

PDB ID: 3DH3