PDB ID: 3DDS
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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26B | O-tert-butyl-N-[(3-{[(2,4,6-trimethylphenyl)carbamoyl]amino}naphthalen-2-yl)carbonyl]-L-threonine | PoSSuM | |||
CFF | Caffeine | PoSSuM | |||
MES | 2-(N-morpholino)-ethanesulfonic acid | PoSSuM | |||
MPD | (4s)-2-methyl-2,4-pentanediol | PoSSuM | |||
PLP | Pyridoxal-5'-phosphate | PoSSuM | |||
PO4 | Phosphate ion | PoSSuM | |||
NBG | N-acetyl-beta-D-glucopyranosylamine | PoSSuM |
Code | Name | Show |
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SEP | Phosphoserine |
Code | Name | Emphasize |
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Code | Name | Show |
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Download interaction data: 3DDS
Structure summary
Code : | 3DDS PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | Crystal structure of glycogen phosphorylase complexed with an anthranilimide based inhibitor GSK261 | ||||||||||||
Release Data : | 2009-01-27 | ||||||||||||
Compound : |
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Source : |
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Authors : | Nolte, R.T. | ||||||||||||
Keywords : | GP, Glycogen Phosphorylase, Diabetes, Allosteric enzyme, Carbohydrate metabolism, Disease mutation, Glycogen metabolism, Glycogen storage disease, Glycosyltransferase, Nucleotide-binding, Phosphoprotein, Pyridoxal phosphate, Transferase | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.80 Å ) | ||||||||||||
Citation : |
Anthranilimide based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. Part 3: X-ray crystallographic characterization, core and urea optimization and in vivo efficacy.
Thomson, S.A.,Banker, P.,Bickett, D.M.
et al.
PubMed: 19138846 |
Reaction
Chain : | A, B | ||||||||
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UniProt : | P06737 (PYGL_HUMAN) | ||||||||
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