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Ligands
Code Name Style Show Link
CS2 D-mannonic acid
MN Manganese (II) ion
Non-standard Residues
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Glycosylation
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Code : 3DBN   PDBj   RCSB PDB   PDBe
Header : LYASE
Title : Crystal structure of the Streptoccocus suis serotype2 D-mannonate dehydratase in complex with its substrate
Release Data : 2009-06-23
Compound :
mol_id molecule chains synonym
1 Mannonate dehydratase A,B D-mannonate hydrolase
ec: 4.2.1.8
Source :
mol_id organism_scientific expression_system
1 Streptococcus suis  (taxid:391295) Escherichia coli BL21  (taxid:511693)
strain: 05ZYH33
gene: uxuA, SSU05_1157
expression_system_strain: BL21
expression_system_vector_type: plasmid
expression_system_plasmid: pET28b
Authors : Peng, H., Zhang, Q., Gao, F., Gao, G.F.
Keywords : TIM Barrel, Lyase
Exp. method : X-RAY DIFFRACTION ( 2.90 Å )
Citation :

Crystal structures of Streptococcus suis mannonate dehydratase (ManD) and its complex with substrate: genetic and biochemical evidence for a catalytic mechanism

Zhang, Q.,Gao, F.,Peng, H.  et al.
(2009)  J.Bacteriol.  191 : 5832 - 5837

PubMed: 19617363
DOI: 10.1128/JB.00599-09

Chain : A, B
UniProt : A4VVI4 (UXUA_STRSY)
Reaction: EC: Evidence:
Physiological Direction:
D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O 4.2.1.8 HAMAP- Rule:MF_00106
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