Het-PDB Navi2 (PDB: 3D4V)

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Ligands
Code	Name		Style	Show	Link

Non-standard Residues
Code	Name	Show
FMG	2-amino-9-(2-deoxy-2-fluoro-5-O-phosphono-beta-D-arabinofuranosyl)-7-methyl-6-oxo-6,9-dihydro-1h-purin-7-ium

Glycosylation
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Modification
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Download interaction data: 3D4V

Code :

3D4V PDBj RCSB PDB PDBe

Header :

HYDROLASE/DNA

Title :

Crystal Structure of an AlkA Host/Guest Complex N7MethylGuanine:Cytosine Base Pair

Release Data :

2008-09-09

Compound :

mol_id	molecule	chains	synonym
1	DNA-3-methyladenine glycosylase 2	A,B,C,D	DNA-3-methyladenine glycosylase II, 3-methyladenine-DNA glycosylase II, inducible, TAG II, DNA-3-methyladenine glycosidase II
	ec: 3.2.2.21

mol_id	molecule	chains
2	5'-D(DGPDAPDCPDAPDTPDGPDAP(FMG)PDTPDGPDCPDC)-3'	E,G

mol_id	molecule	chains
3	5'-D(DGPDGPDCPDAPDCPDTPDCPDAPDTPDGPDTPDC)-3'	F,H

Source :

mol_id	organism_scientific	expression_system
1	Escherichia coli (taxid:562)	Escherichia coli
	gene: alkA, aidA, b2068, JW2053 expression_system_strain: BL21(DE3) expression_system_vector_type: plasmid expression_system_plasmid: pET30

mol_id	organism_scientific
2
	synthetic: yes

mol_id	organism_scientific
3
	synthetic: yes

Authors :

Lee, S., Bowman, B.R., Wang, S., Verdine, G.L.

Keywords :

AlkA, N7MethylGuanine, DNA repair, host-guest complex, DNA structure, DNA damage, Hydrolase, HYDROLASE-DNA COMPLEX

Exp. method :

X-RAY DIFFRACTION ( 2.900 Å )

Citation :

Synthesis and structure of duplex DNA containing the genotoxic nucleobase lesion N7-methylguanine.

Lee, S.,Bowman, B.R.,Ueno, Y. et al.
(2008) J.Am.Chem.Soc. 130 : 11570 - 11571

PDB ID: 3D4V