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Ligands
Code Name Style Show Link
ANP Phosphoaminophosphonic acid-adenylate ester
FCN Fosfomycin
MG Magnesium ion
Non-standard Residues
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Glycosylation
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Code : 3D41   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal structure of fosfomycin resistance kinase FomA from Streptomyces wedmorensis complexed with MgAMPPNP and fosfomycin
Release Data : 2008-08-12
Compound :
mol_id molecule chains
1 FomA protein A
Source :
mol_id organism_scientific expression_system
1 Streptomyces wedmorensis  (taxid:43759) Escherichia coli  (taxid:562)
gene: fomA
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pET28b
Authors : Pakhomova, S., Bartlett, S.G., Augustus, A., Kuzuyama, T., Newcomer, M.E.
Keywords : fosfomycin, antibiotic resistance, kinase, phosphoryl transfer, Transferase
Exp. method : X-RAY DIFFRACTION ( 2.20 Å )
Citation :

Crystal Structure of Fosfomycin Resistance Kinase FomA from Streptomyces wedmorensis.

Pakhomova, S.,Bartlett, S.G.,Augustus, A.  et al.
(2008)  J.Biol.Chem.  283 : 28518 - 28526

PubMed: 18701452
DOI: 10.1074/jbc.M803709200

Chain : A
UniProt : Q56187 (Q56187_STRWE)
Reaction: EC: Evidence:
Physiological Direction:
ATP + isopentenyl phosphate = ADP + isopentenyl diphosphate 2.7.4.26 ARBA:ARBA00000538
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