Het-PDB Navi2 (PDB: 3CVW)

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Ligands
Code	Name		Style	Show	Link
FAD	Flavin-adenine dinucleotide				PoSSuM
FO1	1-deoxy-1-(8-hydroxy-2,4-dioxo-3,4-dihydropyrimido[4,5-B]quinolin-10(2h)-yl)-D-ribitol				PoSSuM

Non-standard Residues
Code	Name	Show
5PY	1-(2'-deoxy-5'-O-phosphono-beta-D-erythro-pentofuranosyl)-5-methylpyrimidin-2(1h)-one
64T	5-hydroxy-thymidine-5'-monophosphate

Glycosylation
Code	Name	Emphasize

Modification
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Download interaction data: 3CVW

Code :

3CVW PDBj RCSB PDB PDBe

Header :

Lyase/DNA

Title :

Drosophila melanogaster (6-4) photolyase H365N mutant bound to ds DNA with a T-T (6-4) photolesion and cofactor F0

Release Data :

2009-10-13

Compound :

mol_id	molecule	chains
1	DNA (5'-D(DAPDCPDAPDGPDCPDGPDGP(64T)P(5PY)PDGPDCPDAPDGPDGP*DT)-3')	C
	other_details: DNA with (6-4) photolesion

mol_id	molecule	chains
2	DNA (5'-D(DTPDAPDCPDCPDTPDGPDCPDAPDAPDCPDCPDGPDCPDTP*DG)-3')	D

mol_id	molecule	chains
3	RE11660p	A
	mutation: H365N

Source :

mol_id	organism_scientific
1
	synthetic: yes

mol_id	organism_scientific
2
	synthetic: yes

mol_id	organism_scientific	expression_system
3	Drosophila melanogaster (taxid:7227)	Escherichia coli (taxid:562)
	gene: phr64-520 expression_system_strain: Rosetta-gami pLysS (DE-3) expression_system_vector_type: PLASMID expression_system_plasmid: derived from pDEST007

Authors :

Maul, M.J., Barends, T.R.M., Glas, A.F., Cryle, M.J., Schlichting, I., Carell, T.

Keywords :

DNA repair, Lyase-DNA COMPLEX

Exp. method :

X-RAY DIFFRACTION ( 3.20 Å )

Citation :

Structure and mechanism of a cofactor f0 accelerated (6-4) photolyase from the fruit fly

Maul, M.J.,Barends, T.,Glas, A.F. et al.
To be Published

PDB ID: 3CVW