PDB ID: 3CV6
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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NAP | Nadp nicotinamide-adenine-dinucleotide phosphate | PoSSuM | |||
HXS | 4-[(1r,2s)-1-ethyl-2-(4-hydroxyphenyl)butyl]phenol | PoSSuM | |||
BME | Beta-mercaptoethanol | PoSSuM |
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Download interaction data: 3CV6
Structure summary
Code : | 3CV6 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE | ||||||||||||
Title : | The crystal structure of mouse 17-alpha hydroxysteroid dehydrogenase GG225.226PP mutant in complex with inhibitor and cofactor NADP+. | ||||||||||||
Release Data : | 2009-03-03 | ||||||||||||
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Authors : | Dhagat, U., El-Kabbani, O. | ||||||||||||
Keywords : | Aldo-keto reductase, Hydroxysteroid Dehydrogenase, Ternary Complex, Hexestrol, Lipid metabolism, NADP, Oxidoreductase, Phosphoprotein, Steroid metabolism | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.10 Å ) | ||||||||||||
Citation : |
Structure of the G225P/G226P mutant of mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) ternary complex: implications for the binding of inhibitor and substrate.
Dhagat, U.,Endo, S.,Mamiya, H.
et al.
PubMed: 19237748 |
Reaction
Chain : | A, B | ||||||||||||
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UniProt : | Q91WR5 (AK1CL_MOUSE) | ||||||||||||
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