Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
0CO (1s,3r,5z,7e,14beta,17alpha,23r)-23-(2-hydroxy-2-methylpropyl)-20,24-epoxy-9,10-secochola-5,7,10-triene-1,3-diol
Code : 3CS6
Header : GENE REGULATION
Title : Structure-based design of a superagonist ligand for the vitamin D nuclear receptor
Release Data : 2008-05-27
Compound :
mol_id molecule chains synonym
1 Vitamin D3 receptor A VDR, 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1
fragment: UNP residues 118-427
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli
gene: VDR, NR1I1
expression_system_vector: BL21DE3
Authors : Hourai, S., Rodriguez, L.C., Antony, P., Reina-San-Martin, B., Ciesielski, P., Magnier, B.C., Schoonjans, K., Mourino, A., Rochel, N., Moras, D.
Keywords : VDR, agonist, Disease mutation, DNA-binding, Metal-binding, Nucleus, Phosphoprotein, Polymorphism, Receptor, Transcription, Transcription regulation, Zinc, Zinc-finger, GENE REGULATION
Exp. method : X-RAY DIFFRACTION ( 1.8 Å )
Citation :

Structure-based design of a superagonist ligand for the vitamin d nuclear receptor.

Hourai, S.,Rodrigues, L.C.,Antony, P.  et al.
(2008)  Chem.Biol.  15 : 383 - 392

PubMed: 18420145
DOI: 10.1016/j.chembiol.2008.03.016

Chain : A
UniProt : P11473 (VDR_HUMAN)
Reaction : -