Brand  (β version)

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Ligands
Code Name Link
C7P Cis-diammine(pyridine)chloroplatinum(II)
Code : 3CO3
Header : DNA
Title : X-Ray Crystal Structure of a Monofunctional Platinum-DNA Adduct, cis-{Pt(NH3)2(pyridine)}2+ Bound to Deoxyguanosine in a Dodecamer Duplex
Release Data : 2008-06-10
Compound :
mol_id molecule chains
1 5'-D(*DCP*DCP*DTP*DCP*DTP*DCP*DGP*DTP*DCP*DTP*DCP*DC)-3' A
mol_id molecule chains
2 5'-D(*DGP*DGP*DAP*DGP*DAP*DCP*DGP*DAP*DGP*DAP*DGP*DG)-3' B
Source :
mol_id organism_scientific
1
synthetic: yes
mol_id organism_scientific
2
synthetic: yes
Authors : Lovejoy, K.S., Todd, R.C., Zhang, S., McCormick, M.S., D'Aquino, J.A., Reardon, J.T., Sancar, A., Giacomini, K.M., Lippard, S.J.
Keywords : PLATINUM-DNA DUPLEX, CISPLATIN, MONOFUNCTIONAL PT COMPOUND, DNA
Exp. method : X-RAY DIFFRACTION ( 2.160 Å )
Citation :

cis-Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects.

Lovejoy, K.S.,Todd, R.C.,Zhang, S.  et al.
(2008)  Proc.Natl.Acad.Sci.Usa  105 : 8902 - 8907

PubMed: 18579768
DOI: 10.1073/pnas.0803441105