Het-PDB Navi2 (PDB: 3CO3)

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Ligands
Code	Name		Style	Show	Link
C7P	Cis-diammine(pyridine)chloroplatinum(II)				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 3CO3

Code :

3CO3 PDBj RCSB PDB PDBe

Header :

DNA

Title :

X-Ray Crystal Structure of a Monofunctional Platinum-DNA Adduct, cis-{Pt(NH3)2(pyridine)}2+ Bound to Deoxyguanosine in a Dodecamer Duplex

Release Data :

2008-06-10

Compound :

mol_id	molecule	chains
1	5'-D(DCPDCPDTPDCPDTPDCPDGPDTPDCPDTPDCPDC)-3'	A

mol_id	molecule	chains
2	5'-D(DGPDGPDAPDGPDAPDCPDGPDAPDGPDAPDGPDG)-3'	B

Source :

mol_id	organism_scientific
1
	synthetic: yes

mol_id	organism_scientific
2
	synthetic: yes

Authors :

Lovejoy, K.S., Todd, R.C., Zhang, S., McCormick, M.S., D'Aquino, J.A., Reardon, J.T., Sancar, A., Giacomini, K.M., Lippard, S.J.

Keywords :

PLATINUM-DNA DUPLEX, CISPLATIN, MONOFUNCTIONAL PT COMPOUND, DNA

Exp. method :

X-RAY DIFFRACTION ( 2.160 Å )

Citation :

cis-Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects.

Lovejoy, K.S.,Todd, R.C.,Zhang, S. et al.
(2008) Proc.Natl.Acad.Sci.Usa 105 : 8902 - 8907

PDB ID: 3CO3