Brand  (β version)

PDB ID: 3BL6

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Ligands
Code Name Style Show Link
FMC (1s)-1-(7-amino-1h-pyrazolo[4,3-D]pyrimidin-3-yl)-1,4-anhydro-D-ribitol PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 3BL6   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Crystal structure of Staphylococcus aureus 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase in complex with formycin A
Release Data : 2008-06-10
Compound :
mol_id molecule chains
1 5'-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase A
ec: 3.2.2.9, 3.2.2.16
Source :
mol_id organism_scientific expression_system
1 Staphylococcus aureus Escherichia coli
strain: MRSA 703
gene: pfs
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pET28a
Authors : Siu, K.K.W., Lee, J.E., Smith, G.D., Horvatin, C., Howell, P.L.
Keywords : nucleosidase, MTAN, alpha and beta proteins, HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 1.700 Å )
Citation :

Structure of Staphylococcus aureus 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Siu, K.K.,Lee, J.E.,Smith, G.D.  et al.
(2008)  Acta Crystallogr.,Sect.F  64 : 343 - 350

PubMed: 18453700
DOI: 10.1107/S1744309108009275

Reaction

Chain : A
UniProt : Q99TQ0 (MTNN_STAAM)
Reaction: EC: Evidence:
Physiological Direction:
H2O + S-adenosyl-L-homocysteine = adenine + S-(5-deoxy-D- ribos-5-yl)-L-homocysteine 3.2.2.9 HAMAP-Rule:MF_01684
-
H2O + S-methyl-5'-thioadenosine = 5-(methylsulfanyl)-D-ribose + adenine 3.2.2.9 HAMAP-Rule:MF_01684
-
5'-deoxyadenosine + H2O = 5-deoxy-D-ribose + adenine 3.2.2.9 HAMAP-Rule:MF_01684
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