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Ligands
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DS3 5-{4-[3-(4-{[(2r)-2-hydroxy-3,3-dimethylbutyl]oxy}-3-methylphenyl)pentan-3-yl]-2-methylphenoxy}pentanoic acid
Non-standard Residues
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Glycosylation
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Code : 3AZ2   PDBj   RCSB PDB   PDBe
Header : HORMONE RECEPTOR
Title : Crystal Structure Analysis of Vitamin D receptor
Release Data : 2011-11-02
Compound :
mol_id molecule chains synonym
1 Vitamin D3 receptor A VDR, 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1
fragment: UNP RESIDUES 120-164, 216-423
other_details: fusion protein of residues 120-164 and residues 216-423
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: NR1I1, VDR
Authors : Itoh, S., Iijima, S.
Keywords : Vitamin D receptor, HORMONE RECEPTOR
Exp. method : X-RAY DIFFRACTION ( 1.6900 Å )
Citation :

Novel nonsecosteroidal vitamin D(3) carboxylic acid analogs for osteoporosis, and SAR analysis.

Kashiwagi, H.,Ono, Y.,Shimizu, K.  et al.
(2011)  Bioorg.Med.Chem.  19 : 4721 - 4729

PubMed: 21795053
DOI: 10.1016/j.bmc.2011.07.001

Chain : A
UniProt : P11473 (VDR_HUMAN)
Reaction : -