Brand  (β version)

PDB ID: 3ATR

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Ligands
Code Name Style Show Link
DD9 Nonane PoSSuM
FDA Dihydroflavine-adenine dinucleotide PoSSuM
PPV Pyrophosphate PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 3ATR   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Geranylgeranyl Reductase (GGR) from Sulfolobus acidocaldarius co-crystallized with its ligand
Release Data : 2011-05-04
Compound :
mol_id molecule chains synonym
1 Conserved Archaeal protein A geranylgeranyl reductase
Source :
mol_id organism_scientific expression_system
1 Sulfolobus acidocaldarius  (taxid:2285) Escherichia coli  (taxid:562)
gene: Saci_0986
expression_system_vector_type: plasmid
expression_system_plasmid: pET16b
Authors : Fujihashi, M., Sasaki, D., Iwata, Y., Yoshimura, T., Hemmi, H., Miki, K.
Keywords : Saturating double bonds, archaeal membrane precursor, like 2, 3-di-O-geranylgeranylglyceryl phosphate, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 1.80 Å )
Citation :

Structure and mutation analysis of archaeal geranylgeranyl reductase

Sasaki, D.,Fujihashi, M.,Iwata, Y.  et al.
(2011)  J.Mol.Biol.  409 : 543 - 557

PubMed: 21515284
DOI: 10.1016/j.jmb.2011.04.002

Reaction

Chain : A
UniProt : Q4JA33 (GGR_SULAC)
Reaction: EC: Evidence:
Physiological Direction:
8 A + a 2,3-bis-O-phytanyl-sn-glycerol 1-phospholipid = a 2,3- bis-O-(geranylgeranyl)-sn-glycerol 1-phospholipid + 8 AH2 - PubMed:18375567, PubMed:24954619
right-to-left PubMed:18375567
2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 A = 2,3-bis- O-(geranylgeranyl)-sn-glycerol 1-phosphate + 8 AH2 - PubMed:18375567
right-to-left
4 A + sn-3-O-phytanylglycerol 1-phosphate = 4 AH2 + sn-3-O- (geranylgeranyl)glycerol 1-phosphate - PubMed:18375567
right-to-left
3 A + phytyl diphosphate = (2E,6E,10E)-geranylgeranyl diphosphate + 3 AH2 - PubMed:18375567, PubMed:24954619
right-to-left PubMed:18375567