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Ligands
Code Name Style Show Link
D12 Dodecane
FEE N-{(1s,2s,3r)-1-[(alpha-D-galactopyranosyloxy)methyl]-2,3-dihydroxyoctyl}tetracosanamide
PEG Di(hydroxyethyl)ether
Non-standard Residues
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Glycosylation
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NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
Modification
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Code : 3ARB   PDBj   RCSB PDB   PDBe
Header : IMMUNE SYSTEM
Title : Ternary crystal structure of the NKT TCR-CD1d-alpha-galactosylceramide analogue-OCH
Release Data : 2011-03-30
Compound :
mol_id molecule chains
1 Antigen-presenting glycoprotein CD1d1 A
fragment: heavy chain
mol_id molecule chains
2 Beta-2-microglobulin B
mol_id molecule chains
3 NKT Valpha14-Jalpha18,NKT Valpha14-Jalpha18 C
other_details: Chimera of mouse variable domain and human constant domain,Chimera of mouse variable domain and human constant domain
mol_id molecule chains
4 NKT Vbeta8.2,NKT Vbeta8.2 D
other_details: Chimera of mouse variable domain and human constant domain,Chimera of mouse variable domain and human constant domain
Source :
mol_id organism_scientific organism_common expression_system
1 Mus musculus  (taxid:10090) Mouse Trichoplusia ni  (taxid:7111)
gene: Cd1d1, Cd1.1
expression_system_common: Cabbage looper
expression_system_vector_type: Baculovirus
expression_system_plasmid: pBacP10PH
mol_id organism_scientific organism_common expression_system
2 Mus musculus  (taxid:10090) Mouse Trichoplusia ni  (taxid:7111)
gene: B2m
expression_system_common: Cabbage looper
expression_system_vector_type: Baculovirus
expression_system_plasmid: pBacP10PH
mol_id organism_scientific organism_common expression_system
3 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
expression_system_vector_type: Plasmid
expression_system_plasmid: pET
mol_id organism_scientific organism_common expression_system
4 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
expression_system_vector_type: Plasmid
expression_system_plasmid: pET
Authors : Wun, K.S., Rossjohn, J.
Keywords : mouse NKT TCR, mouse CD1d, IMMUNE SYSTEM
Exp. method : X-RAY DIFFRACTION ( 2.70 Å )
Citation :

A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells

Wun, K.S.,Cameron, G.,Patel, O.  et al.
(2011)  Immunity  34 : 327 - 339

PubMed: 21376639
DOI: 10.1016/j.immuni.2011.02.001

Chain : A
UniProt : P11609 (CD1D1_MOUSE)
Reaction : -
Chain : B
UniProt : P01887 (B2MG_MOUSE)
Reaction : -